Stainless Steel
Mammalian Cell Culture Bioreactor
Over 25 years production experience
Your Reliable Chinese Cell Culture Bioreactor Manufacturer : Bailun（BLBIO）
Bailun Biotechnology is a leading cell culture bioreactor manufacturer in China. Products cover all kinds of bioreactors in laboratory, pilot scale and industrial production, including fermenter, animal cell bioreactor, plant cell bioreactor, single use bioreactor, CIP station , liquid dispensing system and disposable reactor, etc. Can produce bioreactor of 0.1L-1000KL volume and technical services, and provide intelligent and personalized comprehensive solutions for bioreactors process. Bailun has a large number of experienced fermentation process, biochemical equipment and chemical technical engineers, many famous experts and scholars as the company’s technical consultants, Bailun forever pursuits to create value for customers, and adhere to customer-centric is the core value of Bailun.
Stainless steel Mammalian Cell Culture Bioreactor
BLBIO-XSCUC(X means volume liters) is a pilot/industry size mammalian cell culture bioreactor with top magnetic drive, easy operation and clean. Special design impeller with low share and gas(O2/CO2/N2/air) control for good growth of mammalian cell.Standard model control pH/DO/foam/temperature/agitation/4 gas/weighting, four-valve feeding system, tank electrolysis, tank inside poshing 0.2um, sanitary sampling system, gas auto control by mass flow meter optional. Control panel language EN/CN/RU. Mammalian cell culture bioreactor accept customize and design.
Bailun 300L cell culture bioreactor BLBIO-SCUC
Bailun 300L cell culture bioreactor BLBIO-SCUC
Mammalian Cell Culture Bioreactor Can Be Customized
10 inch color touch screen of mammalian cell culture bioreactor displays all measured values and control parameters, usually each bioreactor has 4 peristaltic pumps for acid, alkali, defoamer, medium. Automatic control pH/DO/temperature/agitation/antifoam. Gas has manual control and auto control (mass flow meter) for choose. All fermentation data have history curvy and can export by U disk.
Mammalian cell culture bioreactor have more options: Remote control, Mass flow meter, Exhaust gas (O2/CO2) analysis, Level sensor, Turbidity(OD) sensor, ORP sensor, Glucose detection, Live cell sensor(Biomass), Variable speed pump, Printing, 15” color touch screen, Siemens screen, Program open setting, Tank circulation washing itself, Fermentation data analysis software etc..
Know More About Stainless Steel Cell Culture Bioreactor
| Parameter | Description |
| Total volume | 5L,10L,15L,20L,30L,50L,100L,200L,500L,1000L, 5KL, 10KL etc. |
| Working volume | 30%~70% |
| Tank | Inside electrolytic polishing, precision: 0.2-0.4um. Diameter and height ratio 1:1.5 |
| Stirring system | Magnetic drive, low shear mixing blades. Stir speed: 30~300rpm |
| Sterilization | Sterilize in place (SIP), auto control by program |
| Clean | Clean in place by spray ball |
| Gas control | Provision for mixing at least four gases (Air, Oxygen, Nitrogen and CO2) Auto control by mass flow meter. Air flow 1vvm, O2/N2/CO2 0.1vvm. |
| Feeding | Automatically feeding by peristaltic pump |
| Anti-foam control | Automatically add antifoamer by peristaltic pump |
| Temperature control | Auto-control, electric heating range: water source add 5℃ to 70℃ |
| PH control | PH 2.00-12.00±0.1, auto-control adding acid/base by peristaltic pump, pH sensor from Hamilton/Mettler, Switzerland. |
| Do control | 0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen. |
| Sampling valve | Can sterilization separately, manual |
| Harvest | Zero dead zone bottom valve, can sterilization separately, manual |
| Weight system | Mettler-Toledo, Switzerland |
| Pressure | Auto control, BD Germany pressure transmitter or Lambert differential pressure liquid level gauge. |
| Exhaust | Have condenser before exhaust, control by diagram valve / Proportional control valve. |
| Control parameters | 10 or 15 inch touch screen, Siemens PLC with control parameters (stirring, pH, DO, temperature, feeding, alarm, gas etc.), data analysis, data record, data output, language(RU/EN/CN) and other customized functions |
| Optional configuration | We can customize the parameters of cell culture bioreactor according to customer needs，such as Remote control, Mass flow meter(auto control gas), exhaust heating, exhaust filter, gas(CO2) exhaust analysis, Level sensor, Turbidity(OD) sensor, ORP sensor, Weight system, Live cell sensor（Biomass）, Printing, Siemens touch screen, Double mechanical seal, 4-valves-group for feeding, Bottom valve auto, ASME certificate, CSA certificate, air flow 2vvm, etc. |
The following picture shows the production workshop of Bailun.
Supporting Equipment
The refrigeration system of a chiller unit consists of four basic parts: compressor, condenser, throttle, and evaporator. Connect the four major components in a certain order using copper pipes to form a closed system, which is filled with a certain amount of refrigerant.
The compressor sucks in low-temperature and low-pressure Freon gas from the evaporator, compresses it into high-temperature and high-pressure Freon gas, and then flows through a thermal expansion valve (capillary tube), throttling it into a low-temperature and low-pressure Freon liquid two-phase object. Then, the low-temperature and low-pressure Freon liquid absorbs heat from indoor air in the evaporator, and the cycle of compression condensation throttling evaporation is repeated.
The Bailun steam generator uses well-known imported accessories, which are corrosion-resistant and finely crafted. Fast steam production in one minute, with a thermal efficiency of up to 100.27%. Clean steam, sufficient gas production, can provide stable steam for a long time, ensuring the required heat energy during the drying process. Advanced vertical cross flow structure, using 12Cr1MoVG high-pressure boiler steel and stainless steel laser fins with extremely high heat transfer efficiency, no explosion risk, safer equipment, and better steam quality.
Bailun air compressor is an oil-free and silent air compressor equipped with a domestically produced powerful air pump and a gas tank with built-in anti-corrosion coating. It has a high cost performance and is used as a supporting equipment for bioreactors. Has the following characteristics:
● Independently produce machine heads and components;
The machine is equipped with multiple automatic protection systems for safer use;
● Easy to operate, ready to use upon power connection, automated design, no need for dedicated personnel to operate the work;
●Low noise during work, original oil-free piston system, high efficiency, low loss, and clean gas discharge;
●Optional double-layer vacuum drying and filtering equipment to meet the supply of high-purity air source and protect user equipment;
Cases
30L cell culture bioreactor with chiller and steam generator BLBIO-SCUC
150L cell culture bioreactor BLBIO-SCUC
500L cell culture bioreactor BLBIO-SCUC
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Our Advantages
Extensive experience and expertise
We have many years of experience in the industry and accumulated a wealthof professional knowledge to provide customers with the best quality products and services.
Diverse product lines
We provide products in the field of bioreactor (fermenter) andcomplete control system to provide customers with a full range of solutions.
Strict quality control.
We have always adhered to strict quality management and technological innovation to ensure that our products are always in the leading positionin the industry.
Customer first service concept.
We always stand on the customer's point of view, starting from the customer's needs, to provide customers with the best solution. No matter what customers need, we will meet their needs with a professional attitude and high-quality products.
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