Multistage Stirring Tank Bioreactor
25 Years Experience Bioreactor/Fermenter Manufacturer
Your Reliable Chinese Stirred Tank Bioreactor Manufacturer : Ferbio
Ferbio is a leading bioreactor manufacturer in China.Ferbio produces various types of biological fermenters, capable of producing bioreactors with volumes ranging from 0.1L to 1000KL, and provides technical services to provide intelligent and personalized comprehensive solutions for bioreactor processes. The products provided by Ferbio are classified by scale, there are seed fermenters, pilot scale bioreactors, and industrial scale bioreactors; In terms of usage, there are vaccine bioreactors, cell culture bioreactors, bacterial bioreactors, plant cell bioreactors, etc. In addition, Ferbio also has supporting equipment for bioreactors, such as air compressors, chillers, steam generators, centrifuges, etc. Ferbio has a large team of experienced fermentation process, biochemical equipment, and chemical technology engineers, with many renowned experts and scholars serving as technical consultants for the company. Ferbio always puts customer needs first and insists on putting customers at the center.
Introduction to Stirred Tank Bioreactor
The Parallel Stainless Steel Bioreactor System is a state-of-the-art solution engineered for high-throughput bioprocess development, scale-up optimization, and process reproducibility in industrial and research environments. Designed for parallel operation of multiple individually controlled stainless steel bioreactors, this system is built to support intensive screening, comparative analysis, and pilot-to-production scale studies.
Constructed from pharmaceutical-grade 316L stainless steel, each vessel ensures durability, sterility, and compliance with GMP and ASME standards. With advanced automation, real-time monitoring, and process data integration, this platform enables B2B clients such as biotech manufacturers, pharmaceutical R&D labs, and academic institutions to reduce development cycles, improve process accuracy, and accelerate commercialization.
Key Features and Advantages
1. Multi-Vessel Parallel Operation
Operate 2 to 8 bioreactors simultaneously, with independent or synchronized control of each unit.
Each reactor operates as a standalone unit or as part of a coordinated group for controlled comparative experiments.
Ideal for media optimization, strain evaluation, upstream development, and tech transfer.
2. 316L Stainless Steel Construction with GMP Compliance
All wetted surfaces are constructed using 316L stainless steel with internal surface finish Ra ≤ 0.4 μm.
Conforms to GMP,and ASME requirements for pharmaceutical-grade equipment.
Resistant to corrosion, pressure, and steam sterilization — making it ideal for repeated long-term industrial use.
3. Advanced Control System with Real-Time Monitoring
Fully integrated PLC or touchscreen for real-time parameter control and batch automation.
Each unit independently monitors and adjusts pH, DO, agitation speed, temperature, gas flow, and antifoam levels.
Real-time alarms, data logging, remote access, and 21 CFR Part 11 compliance ready.
4. Precision Environmental Management
Accurate control of temperature (via thermal jackets or external heat exchangers).
Agitators configured for low- or high-shear mixing, depending on culture type (bacteria, yeast, CHO cells, etc.).
Integrated mass flow controllers (MFCs) or rotameters for each bioreactor’s gas inputs (Air, O₂, N₂, CO₂).
5. Full CIP and SIP Compatibility
Supports Clean-in-Place (CIP) and Steam-in-Place (SIP) sterilization without disassembly.
Hygienic design with zero dead-leg zones, drainability, and validated spray ball configurations.
Documentation and validation support provided for GMP inspections and QA records.
6. Flexible Working Volumes and Configurations
Available in working volumes from 5L to 20KL per vessel, with custom sizes available on request.
Modular layout: reactors can be placed on a shared skid or installed individually for maximum flexibility.
Optional sampling ports, optical sensors, pressure transmitters, and automated feed systems enhance usability.
Know More About Parallel Stirred Tank Bioreactor
| Parameter | Description |
| Total volume | 5L~200KL |
| Working volume | 30%~70% |
| Tank | Jacket tank, made by SS316 and SS304, tank design pressure 0.3Mpa, jacket design pressure 0.35Mpa, polishing 0.4-0.6um, ratio of diameter and height is 1:2.2-2.5 |
| Stirring system | Mechanical drive on the top/bottom or Magnetic drive on the top, 3pcs height adjustable six-blade paddle Stir speed: 50~1000rpm/50-400rpm |
| Sterilization | Sterilize in place(SIP), auto control by program |
| Clean | Clean in place (CIP) by spray ball |
| Gas control | Control by rotor meter, air flow 1 vvm |
| Feeding | Automatically feeding by peristaltic pump |
| Anti-foam control | Automatically add antifoam by peristaltic pump |
| Temperature control | Auto-control, electric heating range: water source add 5℃ to 70℃ |
| PH control | PH 2.00-12.00±0.1, auto-control adding acid/base by peristaltic pump, pH sensor from Hamilton/Mettler, Switzerland. |
| Do control | 0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen. |
| Sampling | Sampling valve, can sterilization separately, manual |
| Harvest | Zero dead zone bottom valve(Gemu/Burket,Germany), can sterilization separately, manual/auto |
| Lid lift system | 30L-500L have lid lift system, 700-1000L have human hole. |
| Pressure | Auto control, BD Germany pressure transmitter |
| Exhaust | Have condenser before exhaust, control by diagram valve / Proportional control valve. |
| Control parameters | 10 or 15 inch touch screen , Siemens PLC with control parameters (stirring, pH, DO, temperature, feeding, alarm, gas etc.), data analysis, data record, data output, language(RU/EN/CN) and other customized functions |
| Optional configuration | We can customize the parameters of parallel stirred tank bioreactor ording to customer needs，such as Remote control, Mass flow meter(auto control gas), O2/N2/CO2, gas flow 2vvm, gas(CO2) exhaust analysis, Level sensor, Turbidity(OD) sensor, ORP sensor, Weight system, Live cell sensor(Biomass), Printing, Siemens touch screen, Double mechanical seal, 4-Valves-group for feeding, Bottom valve auto discharge, ASME certificate, CSA certificate, Batch culture, Seed transfer, etc. |
Our Factory
The following picture shows the production workshop of Ferbio.
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Our Advantages
Extensive Manufacturing Experience
With over 20 years of bioreactor production expertise, our factory delivers high-performance systems trusted by global biotech and pharmaceutical companies.
Customized Solutions
We provide tailor-made bioreactor designs to meet diverse application needs, including microbial fermentation, cell culture, and pilot-scale production. ers with a full range of solutions.
Full Range of Products
From lab-scale glass fermenters to industrial stainless steel systems, we offer a complete portfolio to support all stages of bioprocess development.
Global Technical Support
Our experienced engineering and after-sales teams provide responsive service and on-site support worldwide.