Sterilizing in Situ Glass Bioreactor
25 Years Experience Bioreactor/Fermenter Manufacturer
Your Reliable Chinese Sterilizing in Situ Glass Bioreactor Manufacturer : Ferbio
Ferbio is a leading bioreactor manufacturer in China.Ferbio produces various types of biological fermenters, capable of producing bioreactors with volumes ranging from 0.1L to 1000KL, and provides technical services to provide intelligent and personalized comprehensive solutions for bioreactor processes. The products provided by Ferbio are classified by scale, there are seed fermenters, pilot scale bioreactors, and industrial scale bioreactors; In terms of usage, there are vaccine bioreactors, cell culture bioreactors, bacterial bioreactors, plant cell bioreactors, etc. In addition, Ferbio also has supporting equipment for bioreactors, such as air compressors, chillers, steam generators, centrifuges, etc. Ferbio has a large team of experienced fermentation process, biochemical equipment, and chemical technology engineers, with many renowned experts and scholars serving as technical consultants for the company. Ferbio always puts customer needs first and insists on putting customers at the center.
Sterilizing in situ Glass Bioreactor
The In Situ Sterilization Glass Bioreactor is a high-performance bioprocessing solution designed for precise microbial cultivation and cell culture under sterile conditions. Engineered with premium borosilicate glass and stainless steel components, this bioreactor integrates automated in situ sterilization (SIP) capabilities, reducing manual handling, preventing contamination, and ensuring continuous, safe operations. It is ideal for laboratories, research institutes, pilot-scale production, and industrial R&D in biotechnology, pharmaceuticals, environmental engineering, and food industries.
Key Features & Advantages
1. In Situ Sterilization (SIP) System
Automated sterilization through direct steam or electric jacket heating.
Reduces time-consuming manual cleaning and autoclaving processes.
Ensures a closed, sterile environment, minimizing contamination risks.
SIP can be programmed to run in sync with clean-in-place (CIP) procedures.
2. High-Quality Glass Vessel
Borosilicate glass construction with excellent chemical resistance and thermal stability.
Transparent body allows full visual monitoring of culture growth.
Designed to withstand repeated sterilization cycles and pressure fluctuations.
Available in working volumes from 1L to 40L, custom sizes supported.
3. Modular & Customizable Design
Custom ports for sensors (pH, DO, ORP, temp, foam), sampling, gas inlet/outlet, and nutrient feed.
Interchangeable headplates in 316L stainless steel for durability and hygiene.
Designed for easy upgrade or integration with control systems and data logging software.
4. Efficient Mixing & Aeration
Variable-speed motor (brushless DC or servo type) with low noise and high reliability.
Magnetic or mechanical seal drive options, based on user preference.
Integrated sparger and baffle system enhances oxygen transfer rate (OTR).
Suitable for aerobic and anaerobic fermentation processes.
Know More About Sterilizing in situ Glass Bioreactor
| Parameter | Description |
| Total volume | 5L~40L |
| Working volume | 40%~70% |
| Tank | Glass wall with stainless steel lid and bottom, heating from jacket bottom. |
| Stirring system | Mechanical drive(top) or Magnetic drive(top/bottom), 3 six-blade paddle and 1 foam breaker, each paddle height adjustable. Mix speed: 50~1000rpm/50-400rpm |
| Sterilization | Sterilization in situ (SIP), manual |
| Gas control | Control by rotor meter, air flow 2vvm. |
| Feeding | Automatically feeding by peristaltic pump |
| Anti-foam control | Automatically add antifoamer by peristaltic pump |
| Temperature control | Auto-control by program, electric heating range water source add 5℃ to 70℃ |
| PH control | PH 2.00-12.00±0.1, auto-control adding acid/base by peristaltic pump, pH sensor from Hamilton/Mettler, Switzerland. |
| DO control | 0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen. |
| Sampling | Manual sampling |
| Control parameters | 10 or 15 inch touch screen , Siemens PLC with control parameters (stirring, pH, DO, temperature, feeding, alarm, gas etc.), data analysis, data record, data output, language(RU/EN/CN) and other customized functions |
| Optional configuration | We can customize the parameters of sterilizing in situ glass bioreactor according to customer needs，such as Remote control, Mass flow meter(auto control gas), O2/N2/CO2, gas(CO2) exhaust analysis, Level sensor, Turbidity(OD) sensor, ORP sensor, Weighting system, Live cell sensor（Biomass）, Printing, Siemens touch screen, etc. |
Our Factory
The following picture shows the production workshop of Ferbio.
Other Products
Send Inquiry
Our Advantages
Extensive Manufacturing Experience
With over 20 years of bioreactor production expertise, our factory delivers high-performance systems trusted by global biotech and pharmaceutical companies.
Customized Solutions
We provide tailor-made bioreactor designs to meet diverse application needs, including microbial fermentation, cell culture, and pilot-scale production. ers with a full range of solutions.
Full Range of Products
From lab-scale glass fermenters to industrial stainless steel systems, we offer a complete portfolio to support all stages of bioprocess development.
Global Technical Support
Our experienced engineering and after-sales teams provide responsive service and on-site support worldwide.